The LEPS team

Gaëtan DES GUETZ

PU-PH en oncologie médicale

Activités récentes :

Publications récentes : Cinq articles expliquant mes travaux, mes centres d’intérêts

D’abord trois publications concernant des travaux de méta-analyse et de revue systématique évaluant en cancérologie digestive le bénéfice de traitements adjuvants malgré des délais de prise en charge souvent expliqués par des comorbidités ou des problématiques sociales, deuxième article sur la meilleure durée des traitements en situations métastatiques, enfin sur l’évaluation de paramètres biologiques en l’occurrence la vascularisation tumorale. Cet article sur l’intérêt de la densité vasculaire comme facteur pronostique a été cité plus de 500 fois,

Quatrième article soulignant mon intérêt sur les études translationnelles avec l’impact de la chimiothérapie en fonction de cette spécificité moléculaire (statut MSI).

Et un cinquème article sur l’évaluation des thérapies ciblées et des stratégies optimales dans les cancers du côlon métastatiques. Etude en partenariat avec la fédération des cntres anti-cancéreux UNICANCER.

des Guetz G, Nicolas P, Perret GY, Morere JF, Uzzan B. Does delaying chemotherapy after curative surgery for colorectal cancer impair survival ? A meta-analysis. European Journal of Cancer 2010 ; 46(6):1049-55. IF 4.2

des Guetz G, Uzzan B, Morere JF, Perret G, Nicolas P. Duration of adjuvant chemotherapy for patients with non-metastatic colorectal cancer. Revue Cochrane library 2010 ; 20;(1) IF 5.2

G Des Guetz, Uzzan B, Nicolas P, Cucherat M, Morere JF, Benamouzig R, Breau JL, Perret GY. MVD and VEGF expression as prognostic factor of Colorectal Cancer; Meta-Analyses of the literature. British Journal of Cancer Publication 2006 ; 94(12) :1823-32. IF 4,5

Des Guetz G, Mariani P, Cucherousset J, Benamoun M, Lagorce C, Sastre X, Le Toumelin P, Uzzan B, Perret GY, Morere JF, Breau JL, Fagard R, Schischmanoff PO. Microsatellite instability and sensitivitiy to FOLFOX treatment in metastatic colorectal cancer. Anticancer Research 2007; 27(4) : 2715-9

Bennouna J, Hiret S, Bertaut A, Bouché O, Deplanque G, Borel C, François E, Conroy T, Ghiringhelli F, des Guetz G, Seitz JF, Artru P, Hebbar M, Stanbury T, Denis MG, Adenis A, Borg C. Continuation of Bevacizumab vs Cetuximab Plus Chemotherapy After First Progression in KRAS Wild-Type Metastatic Colorectal Cancer: The UNICANCER PRODIGE18 Randomized Clinical Trial. JAMA Oncol. 2018 1;5(1):83-90 IF 20.9

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Laurence FOND-HARMANT

Directrice de Recherche

I lead national and international research projects (Europe and Africa) on e-health and psycho-social approaches and/or policies in public health, psychiatry and mental health.
Areas of work /Vulnerable population, social inequality of health, health promotion, analysis of professional practices, program evaluation.

Activités récentes :

Publications récentes : 1. Kane, H., Gourret Baumgart, J., Fond-Harmant, L. & Denis, F. (2022). Usages des outils numériques en psychiatrie et santé mentale face à la COVID-19 en Europe. Santé Publique, 34 https://doi.org/10.3917/spub.220.0002c

2. Gourret Baumgart, J., Kane, H., Denis, F. & Fond-Harmant, L. (2022). Travailler en contexte d’incertitudes : l’expérience des professionnels de la santé mentale face à la COVID-19. Santé Publique, 34 https://doi.org/10.3917/spub.220.0009e

3. Gourret Baumgart, J., Kane, H, Absil, G., Deloyer, J., El-Hage, W., Fuenzalida, C., Gavrila-Ardelean, Krzysztof, K., Le Saint, L., Marazziti, D., Moraitou, M., Reunanen, M., Rexhaj, S., Thome, J. Fond-Harmant, L., Denis, F. 2022, Lessons learned from the Covid-19 crisis : recommendations for action to optimize occupational health in mental health professionals in Europe, Clinical Neuropsychiatry, 19(4) : 220-229.

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Frédérique TREVIDY

Chercheuse associée au Laboratoire Educations et Pratiques de Santé (Leps) UR 3412 Docteure des sciences de l’éducation ; Directrice du pôle ingénierie sociale de l’ALFI

Having defended my doctoral thesis at LEPS in December 2013, I have been an associate researcher there since then. My research is conducted in the framework of a partnership between LEPS and ALFI, which is an association of the Arcade Vyv group (a social housing group composed of several HLM organizations).
My research themes deal with the construction of an identity relationship between the person and his/her housing, formalized by the concept of "Identity-Housing. The approach is constructivist and is in line with the ecological and systemic model of environmental psychology, placing the individual and his or her dwelling at the center of an environment, with which he or she will interact, develop learning and projections. Our research method is collaborative and involves the people concerned (residents, tenants, social and health workers) in the protocol. We explore the mechanisms of identity construction (cognitive processes, learning, feelings of identity) and propose intervention methods and tools for professionals and tenants in social housing. For example: a person-centered education model, transferable to social housing enterprises, to prevent falls among elderly tenants. Or the proposal of a reflexive tool allowing to question and to make evolve the accompaniment of the residents in boarding houses (identification of conversion factors favouring or limiting the development of housing-identity capabilities).

Activités récentes : Collaborative research with boarding house residents:

Havez, F. (Director). (2020). Housing first: A collaborative research [Documentary]. https://vimeo.com/473315084

Havez, F. (Director). (2022). Outside-In [Documentary]. https://www.allocine.fr/film/fichefilm_gen_cfilm=305362.html

Publications récentes : Trévidy F, Benoist Y, Cocot JP, Cuvilliez P, Le Guen M, Niati A, Gervais M, Petitot, C, et Gagnayre R. Construire son identité-logement après un parcours sans domicile : une recherche participative en pension de famille. RFAS. 2022;juillet-septembre(3).sous presse

Trévidy F, Torrot-Arrocet D, Brunie V, Peyronnie MM, Wolfrom J, Brugidou G, et Gagnayre R. Étude sur la transférabilité d’une intervention d’éducation en santé dans le parc HLM : une méthode de recherche à l’épreuve du transfert pour décrire autrement les fonctions-clés: Global Health Promotion [Internet]. 12 avr 2021 [cité 14 avr 2021]; Disponible sur: https://journals.sagepub.com/eprint/ZZEMY4WX2WAWISJVZXDR/full

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Maria Grazia ALBANO

Professeur agrégé confirmé de la Faculté de Médecine de Bari (Italie) : secteur disciplinaire MED/02 ; enseignements dans la formation de base: « Histoire de la Médecine » et « Education du patient » dans dans la formation de spécialité en Odontologie

- Director of the Center of Pedagogy of Health Sciences, University of Foggia (2003-2021)
- Responsible for the International Master in Therapeutic Patient Education, University of Foggia (2003-2004)
- Coordinator of the Research Doctorate in Didactics of Medicine, University of Foggia (2003-2008)
- Coordinator of the 1st year medical exams in the "Humanities" area, University of Bari (from 2021 to date)

Activités récentes : - Teacher in the Master of Public Health, specialty: "Health Education", University of Paris 13, UE: "Evaluation of Therapeutic Patient Education" (from 2003 to 2011)
- Coordinator of the course "Therapeutic Patient Education" for the ARS (ASL) of Bari
- Coordinator of the Advanced courses: "Therapeutic Patient Education" for the University of Bari (A.A. 2000/01) and Foggia (A.A. 1999/2000- 2001/2002)
- Associate researcher at LEPS since 2003

Publications récentes : - -Albano MG ; Gagnayre R ; De Andrade V ; d’Ivernois JF
L’éducation précédant la sortie de l’hôpital : nouvelle forme d’éducation thérapeutique. Critères de qualité et perspectives d’application à notre contexte
Revue ARSI N° 141, 2020/2, pages 70 à 77
- Albano MG ; d’Ivernois JF ; Langlume L ; Ahouah M ; de la Tribonnière X
L’effet de Halo : quand les patients éduqués éduquent à leur tour leurs aidant

Educ Ther Patient/Ther Patient Educ 2021, 13, 10204
- Riquet S ; Albano MG ; Memoli N ; Zakarian C ; de la Tribonnière X
Préparation à la naissance et à la parentalité : l’effet de Halo ou quand les femmes enceintes éduquées éduquent à leur tour leur conjoint.
Educ Ther Patient/Ther Patient Educ. Volume 14, Number 2, 2022

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Rita Georges NOHRA

chercheure associée à la chaire Recherche Sciences Infirmières

Activités récentes :

Publications récentes : Nohra RG, Morvillers JM, Sacre H, Salameh P, Rothan-Tondeur M. Living with chronic obstructive pulmonary disease in Lebanon: a phenomenological study. East Mediterr Health J. 2022;28(2):114–120. https://doi.org/10.26719/emhj.22.027 ( IF 1.2)

Etude Cérès
Nohra RG, Naim E, Chaaban T, Rothan-Tondeur M. Nurses’ eating habits in Lebanon during the economic and health crises: a cross-sectional study. Archives of Public Health. 2022 Jan 14;80(1):28 (IF 2.3)

Etude Didon
Laffet K, Haboubi F, Elkadri N, Nohra RG & Rothan-tondeur M. The Early Stage of the COVID-19 Outbreak in Tunisia, France, and Germany: A Systematic Mapping Review of the Different National Strategies. International Journal of Environmental Research and Public Health 18(13). August 2021. DOI: 10.3390/ijerph18168622 (IF 2.8)

Etude Nintou
Chandler-Jeanville S, Nohra RG, Loizeau V, Lartigue-Malgouyres C, Zintchem R, Naudin D, Rothan-Tondeur M. Perceptions and Experiences of the COVID-19 Pandemic amongst Frontline Nurses and Their Relatives in France in Six Paradoxes: A Qualitative Study. International Journal of Environmental Research and Public Health 18(13). June 2021. DOI: 10.3390/ijerph18136977 (IF 2.8)

Email : ritag.nohra@gmail.com

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David NAUDIN

Membre associé à la chaire recherche Sciences Infirmières ; Docteur en sciences de l’éducation ; Adjoint du directeur de l’Institut de Formation des Cadres de Santé Coordonnateur du Pôle de la Recherche Paramédicale en Pédagogie du CFDC Pôle Numérique de la Formation – Innovation digitale

David Naudin's work focuses on characterizing the phenomenon of therapeutic compliance and non-compliance in patients with chronic illnesses, using cognitive psychology and neuroscience. His thesis in educational science, under the supervision of Prof. Rémi Gagnayre and Prof. Gérard Reach, entitled "Importance des Fonctions exécutives dans l'observance thérapeutique chez les patients présentant un diabète de type 1" (Importance of executive functions in therapeutic compliance in patients with type 1 diabetes), contributes to a better understanding and characterization of the mechanisms underlying the compliance process in patients with type 1 diabetes.

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Simon-Decap MABAKUTUVANGILANGA NTELA

chercheur associé à la chaire Recherche Sciences Infirmières ; directeur de l'Ecole doctorale ISTM Kindu

Nurse, PhD,
Public Health - Nursing Sciences
Institut Supérieur des Techniques Médicales de Kinshasa
Democratic Republic of Congo

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Taghrid CHAABAN

Chercheure associée à la chaire Recherche Sciences Infirmières ; Directrice de département de Sciences Infirmières à l’université Islamique du Liban ; Professeure associée à la Faculté de Santé Publique à l’université Libanaise.

I have a degree in Nursing, a Masters in Public Health - Epidemiology and Biostatistics, and a PhD in Nursing.
My thesis research aims to understand the role of nurses in the antibiotic prescribing process for the elderly, and to evaluate their role in the strategy for reducing antibiotic use in geriatric facilities.

Activités récentes :

Publications récentes : 1. Chaaban T, Mohsen Y, Ezzeddine Z, Ghssein G. Overview of Yersinia pestis Metallophores: Yersiniabactin and Yersinopine. Biology. 2023; 12(4):598. https://doi.org/10.3390/biology12040598
2. Nohra RG, Chaaban T, Sacre H, Salameh P, Aoun Bacha Z, Le Bon Chami B, Abou Rizk F, Makhlouf P, Rothan-Tondeur M. Evaluating the Feasibility and Pretesting the Impact of an Educational and Telemonitoring Program for COPD Patients in Lebanon. Int J Chron Obstruct Pulmon Dis. 2022 Apr 27; 17:949-965. doi: 10.2147/COPD.S339592. PMID: 35510164; PMCID: PMC9058009.
3. NOHRA, R.G., NAIM, E., CHAABAN, T. and ROTHAN TONDEUR M. (2022) Nurses’ eating habits in Lebanon during the economic and health crises: a cross-sectional study. Arch Public Health 80, 28. https://doi.org/10.1186/s13690-021-00775-1
4. CHAABAN T., HALLAL R., CARROL K. and ROTHAN-TONDEUR M. (2021). Cybernetic Communications: focusing interactions on goal centered care. Nursing Science Quarterly. 34 (1) : 30-32. https://doi.org/10.1177/0894318420965195

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Christian MOUALA

chercheur associé à la chaire Recherche Sciences Infirmières ;

Medical doctor, PhD in Public Health and Epidemiology. United Nations official.

Activités récentes :

Publications récentes : HIV-sensitive social protection: an assessment of east and southern Africa's social protection policies and programmes.
Mokomane Z, Xaba N, Roehm K, Hambayi M, Mumma M, Giordana G, Mabhele S, Mouala C.Afr J AIDS Res. 2023 Jul;22(2):113-122. doi: 10.2989/16085906.2023.2203131. Epub 2023 Jun 20.PMID: 37337841

Good practices for retention in the circuit of prevention of Mother-Child Transmission of HIV in Sub-Saharan Africa: a systematic review of the literature.
De Tomasi K, Mouala C.Med Sante Trop. 2019 Aug 1;29(3):279-286. doi: 10.1684/mst.2019.0911.PMID: 31573523 Free article. English.

[Study of treatment adherence by patients living with HIV in 2009 at the outpatient care and treatment center of Brazzaville, Congo].
Faure N, Diafouka M, Nzounza P, Ekat MH, Mahambou ND, Levasseur G, Tattevin P, Mouala C, Simon B, Mattei JF.Med Trop (Mars). 2011 Oct;71(5):487-91.PMID: 22235624 French.

Assessment of healthcare worker influenza vaccination program in French geriatric wards: a cluster-randomized controlled trial.
Rothan-Tondeur M, Filali-Zegzouti Y, Belmin J, Lejeune B, Golmard JL, de Wazières B, Carrat F, Piette F, Mouala C, Gavazzi G; ORIG association.Aging Clin Exp Res. 2010 Oct-Dec;22(5-6):450-5. doi: 10.1007/BF03337740. Epub 2009 Nov 27.PMID: 19966539 Clinical Trial.

Impact of HIV infection on severity of imported malaria is restricted to patients with CD4 cell counts < 350 cells/microl.
Mouala C, Guiguet M, Houzé S, Damond F, Pialoux G, Viget N, Costagliola D, Le Bras J, Matheron S; FHDH-ANRS CO4 Clinical Epidemiology Group.AIDS. 2009 Sep 24;23(15):1997-2004. doi: 10.1097/QAD.0b013e32832f4215.PMID: 19654499

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Marie-Conception LEOCADIE

chercheure associée à la chaire Recherche Sciences Infirmières

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Catherine de la FOURCHARDIERE

Enseignant-chercheur en Marketing

Catherine de La Fouchardière holds a PhD in Marketing (Management Sciences) from the University of Paris I-Panthéon Sorbonne (2001). She began her career at the University of Versailles-Saint-Quentin, before joining USPN in 2004 in the Marketing Techniques department at the Saint-Denis IUT. There, she took on teaching responsibilities, before heading the Continuing Education and Apprenticeship Department (2014-2016). She is now in charge of Quality in Continuing Education (2017-2019). Trained in pedagogy at SAPIENS-USPC, she obtained the CertifiENS university pedagogy certificate in 2018, and is pursuing research into the valorization of pedagogical commitment, the professional development of teacher-researchers and the evaluation of training systems. This research draws on exchanges within the community of practice she initiated, and with LEPS researchers.

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Christine AMMIRATI

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Paul QUESNAY

Docteur en sciences de l’éducation et de la formation, Ostéopathe DO

QUENAY Paul (Bobigny, France) is an osteopath with a doctorate in education and training. His work focuses on curriculum changes and how to support these changes in healthcare training. He is particularly interested in the implementation of the Approche Par Compétences (APC) and its consequences for individuals, groups and organizations.

Activités récentes : Coordinator, Head of Research for the ANR AVENIR(s) program (France 2030) for the Polytech partnership foundation

Publications récentes : Quesnay, P. Margat, A. (2024) L’Académie Populaire de la Santé, une formation en promotion de la santé par et pour les personnes concernées : proposition d’une meilleure prise en compte des principes de justice épistémique. Education et Socialisation, 74.
Quesnay, P., Poumay, M., & Gagnayre, R. (2022). Accompagner la mise en œuvre de l’approche par compétences dans les formations en santé : Perspectives d’une stratégie de changement pragmatique portée par un individu tercéisateur dans un institut de formation en ostéopathie. Pédagogie Médicale, 23(1), 49‑67. https://doi.org/10.1051/pmed/2022001
Quesnay, P., Cailhol, J., & Falgarone, G. (2021). Osteopathic Manipulative Treatment for Chronic Low Back Pain. JAMA Internal Medicine, 181(8), 1143. https://doi.org/10.1001/jamainternmed.2021.3183
Quesnay, P., Poumay, M., & Gagnayre, R. (2021). How does French initial osteopathic training value relational competency, patient education, and the competency-based approach ? A cross-sectional survey. International Journal of Osteopathic Medicine, 42, 43‑50. https://doi.org/10.1016/j.ijosm.2021.10.002
Quesnay, P., & Gagnayre, R. (2015). Enquête sur la pratique du conseil auprès des ostéopathes français : Vers une pratique d’éducation thérapeutique ? Education Thérapeutique du Patient - Therapeutic Patient Education, 7(1), 10105. https://doi.org/10.1051/tpe/2015003

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Jérome FOUCAUD

Docteur en sciences de l’éducation ; Responsable du département SHS et santé publique à l’institut national du cancer

With a doctorate in educational sciences, I have been head of the SHS and public health department at the French National Cancer Institute since 2017, where I am responsible for developing research and directing studies. Author of some sixty publications, my work focuses on the analysis of health perceptions, health education interventions and therapeutic education.
As a lecturer at Bordeaux University in M2 health psychology, M2 health promotion and M2 health promotion at Lyon 1 University, I teach therapeutic education, project methodology and prevention policies.

Activités récentes : Chairman of Promotion santé Ile de France - member of the Board of Directors of UNIRES, - member of the Haut Conseil de la Santé Publique (High Council for Public Health)

Publications récentes : Khalis M, Elbadisy I, Bouaddi O, Luo A, Bendriouich A, Addahri B, Charaka H, Chahboune M, Foucaud J, Badou A, Belyamani L, Huybrechts I Cluster analysis of cancer knowledge, attitudes and behaviors in the Moroccan population BMC Cancer. 2024; 24: 669. Published online 2024 Jun 1. doi: 10.1186/s12885-024-12226-5PMCID: PMC11143602

Guillemin, A. F., Cervenka, I., & Foucaud, J. Recherche interventionnelle et dispositifs de soutien aux personnes touchées par un cancer et leur entourage: résultats d’une analyse descriptive Intervention. 2023. Psycho-Oncologie, 17(3), 11, p.114-121. https://www.sciencedirect.com/org/science/article/pii/S1778379823000106


Faury, S., Aurouet, P., Quintard, B., & Foucaud, J.
A Systematic Review on Reporting of Methods in National Surveys about Adults' Attitudes to Lifestyle and Environmental Risk Factors for Cancer. 2023. International Journal of Environmental Research and Public Health, 20(9), 5755, p. 1-22.

Le Mao, R., Tromeur, C., Lacut, K., Couturaud, F., Foucaud, J., & Leroyer, C. Attentes des patients asthmatiques vis à vis de leur prise en charge. Revue Française des maladies respiratoires. 2021, p 514-523
https://www.sciencedirect.com/science/article/abs/pii/S0761842521001637

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Aude-Marie FOUCAUT

Chercheure associée, spécialiste de l'Activité Physique Adaptée et Santé (APA-S)

I carry out my research in the field of Public Health in order to evaluate - beyond the effect of physical activity - its feasibility, obstacles and facilitators in the field of health.

Activités récentes : Active lifestyle is a complex health behavior, determined by many factors at micro, meso and macro environmental levels. Our current research aims to increase our knowledge of these factors and to explain them within ecological models. Thanks to the experience gained at the Health & Wellness Lab of the University of Calgary (Alberta, Canada) during a CRCT from 2022 to 2023, and based on the results of previous studies, we will be able to implement projects in France based on implementation science, with large samples of patients. We will then be able to document variables that are unfortunately still under-evaluated in multimodal programs promoting physical activity in secondary and tertiary prevention, such as acceptability, adoption, feasibility, fidelity, safety, reach, sustainability, integration into the care pathway, and cost.

Publications récentes : Ouvrage :
- Foucaut A-M (coord), Chapelot D, Vergnault M, Landry A, Ordonnances en Activité Physique Adaptée : 100 prescriptions, Paris, Maloine, 2nde édition, 2024. 584 pages

Chapitre d’ouvrage :
- Foucaut A-M, Activité physique, santé et éducation thérapeutique du patient chronique, in 4ème éd. Education thérapeutique – Prévention et maladies chroniques, coord. Simon D, Bourdillon F, Popelier M, Grimaldi A, coll. Abrégés de médecine, Paris, Elsevier Masson, 19 août 2020. 432 pages.

Revues internationales :
- Aumaitre A, Gagnayre R, Foucaut A-M, Determinants and factors of physical activity after oncology treatments (DE FACTO) in metropolitan France: Study protocol of mixed method study, JMIR Research Protocols, 2024, 13:e52274

- Aumaitre A, Gagnayre R, Foucaut A-M, Determinants and factors of physical activity and sedentary behaviors among post-treatment breast, colorectal, lung, and prostate cancer survivors living in France: results from the DEFACTO study first phase, Patient Education and Counselling, 2024, 124:108273

- Wagoner CW, Dreger J, Keats MR, Santa Mina D, McNeely ML, Cuthbert C, Capozzi LC, Francis GJ, Trinh L, Sibley D, Langley J, Chiekwe J, Ester M, Foucaut A-M, Culos-Reed SN. First year implementation of the EXercise for Cancer to Enhance Living Well (EXCEL) study: Building networks to support rural and remote community access to exercise oncology resources. International Journal of Environmental Research and Public Health, 2023, 20(3), 1930

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